Robotic Neuronavigation for Precision TMS
Orion™
More than navigation — an intelligent treatment platform. Orion integrates robotics, optical tracking, advanced navigation, workflow automation and treatment documentation to make every transcranial magnetic stimulation session precise, reproducible and documented. Precision. Reproducibility. Confidence.
Sub-mm
Robotic positioning accuracy
Real-time
Optical tracking & motion compensation
MRI + MRI-less
Two navigation modes, one system
6 steps
Registration to automatic session report
Clinical Rationale
Every Millimeter Matters
The therapeutic effectiveness of TMS depends on stimulating the correct cortical target with consistent position, orientation and contact throughout every session. Even small deviations can alter the induced electric field and contribute to variability in treatment delivery.
The limits of manual coil positioning
Targeting Sensitivity
Small errors may shift stimulation to unintended cortical regions.
Head Movement
Unavoidable during treatment; degrades coil-to-target alignment.
Operator Fatigue
Holding the coil in position for 20–40 minutes is physically demanding.
Coil Drift & Contact Pressure
Unintentional movement degrades stimulation accuracy over time.
Operator Variability
Manual positioning differs between clinicians and sessions.
Inconsistent Documentation
Manual records lack the precision needed for quality assurance.
The Platform
A Complete Navigation Ecosystem — Not Simply a Robotic Arm
Metis Orion integrates robotics, optical tracking, advanced navigation, workflow automation and treatment documentation into one clinical platform.
Navigation Software
Intelligent planning and guidance based on individual patient anatomy.
Optical Tracking
High-precision camera tracking of patient and coil throughout treatment.
Robotic Arm
Automated, sub-millimeter positioning of the TMS coil.
Patient & TMS Coil
Target interface and stimulation delivery.
Maintaining accuracy throughout treatment
Unlike static mechanical holders, Orion continuously tracks patient movement and automatically maintains the desired coil position and orientation for the entire session.
Automatic Movement Compensation
Real-time correction for involuntary head motion.
Stable Coil Orientation
Consistent angle and contact pressure maintained automatically.
Reduced Operator Workload
The clinician monitors treatment instead of manually holding the coil.
Workflow
From Planning to Treatment
Every step is guided, tracked, verified and documented — Plan, Navigate, Treat, Report.
01
Patient Registration
Register patient identity and link to the clinical record.
02
MRI Import (Optional)
Import the patient MRI for personalized anatomical targeting.
03
Target Definition
Define the cortical target using anatomical landmarks or coordinates.
04
Automatic Robot Positioning
The system moves the robotic arm to the defined target.
05
Real-Time Navigation & Treatment
Continuous optical tracking maintains accuracy during stimulation.
06
Automatic Session Report
Treatment parameters are documented and saved automatically.
Software Intelligence
A Live Operating Room for the Brain
Orion’s software turns a treatment session into a controlled, instrumented procedure — with real-time 3D visualization, continuous coil alignment feedback, contact-pressure monitoring and a full readiness review before a single pulse is delivered.
Real-time treatment visualization
During stimulation, the operator follows the whole procedure on one screen: a 3D brain model with the stimulation field, live coil alignment, coil-head contact pressure and session progress.
3D Stimulation Field
Color-coded mapping of the induced field over the patient anatomy.
Coil Alignment Monitor
Live RMS distance and Z-offset versus the planned target, with a crosshair alignment view.
Coil-Head Contact Pressure
Continuous graph of contact force in Newtons, with reference thresholds.
Session Progress
Pulses delivered vs. planned and elapsed vs. planned session time, at a glance.
Review readiness before stimulation
Before stimulation begins, Orion runs a complete readiness review. Required checks must pass; warnings are surfaced but allow the clinician to continue if acceptable. Position and angle errors are measured against explicit tolerances.
Required checks
Patient, Target, Protocol, Calibration, Robotic Arm, Camera Tracking, Safety Zone, Landing Object.
Warnings
Optional items flagged for clinician review (e.g. target scene still loading).
Targeting tolerance
Position error measured against a 3.0 mm limit; angle error against a 5.0° limit.
Live coil alignment
RMS distance and Z-offset tracked against the planned target in real time.
Position & angle tolerance
Position error limit 3.0 mm; angle error limit 5.0° — measured, not assumed.
Contact pressure monitoring
Coil-head contact force graphed continuously throughout the session.
Full readiness review
Eight-point checklist verified before every stimulation.
Multi-planar MRI views
Sagittal, coronal and axial views aligned to the target.
Automatic session report
Pulses, time, targeting and pressure data captured automatically.
Flexibility
Adaptable to Your Clinical Workflow
Start with MRI-less navigation and expand to fully personalized MRI-guided treatment as your practice evolves.
MRI-Based Navigation
- Patient-specific anatomy
- Maximum precision
- Ideal for complex cases
- Requires patient MRI
MRI-less Navigation
- Standardized anatomical model
- Fast setup
- No patient MRI required
- Ideal for rapid deployment
Compatible with
•Various TMS stimulators and coil types
•Clinical and research protocols
•Academic hospital and private practice settings
Product Views
Key Features
Robotic Precision
Fully automated robotic arm for consistent, precise coil positioning
Computer-Based Control
Advanced software for programmable treatment protocols
Point-by-Point Targeting
Magnetic brain stimulation with precise, individualized targeting
Product Visualization
Orion™ Navigation
MRI-guided neuronavigation system
Sub-millimeter accuracy
Detailed Specifications
Data & Knowledge
Beyond Navigation — Every Treatment Creates Knowledge
Orion records navigation data, target location, coil orientation, session history and treatment parameters in every session, turning each treatment into structured clinical knowledge that compounds over time.
Treatment
Session delivered with robotic precision
Data
Navigation, target, coil and parameter data captured automatically
Insights
Patterns emerge across sessions and patients
Better Decisions
Clinicians and organizations improve outcomes over time
Better Accuracy
Patient-specific targeting directs stimulation to the intended cortical region.
Better Reproducibility
Consistent positioning across all sessions and operators.
Better Workflow
Reduced setup time and simplified operation.
Better Documentation
Automatic recording of parameters supports quality assurance.
Engineering performance, measured
Quantitative performance data collected under standardized laboratory and clinical conditions, with full traceability per risk-management documentation.
≤ 1.2 mm
Targeting accuracy
Mean Euclidean deviation between planned and delivered coil position across the corticospinal target volume.
≤ 0.4 mm
Repeatability
Standard deviation of coil placement across repeated automated positioning cycles at a fixed target.
6 DOF
Pose stability
Six-degree-of-freedom pose maintained throughout stimulation, with continuous closed-loop correction.
≥ 99.5%
Session continuity
Automated recovery and pose re-acquisition rate across interrupted treatment sessions.
Outcomes supported by clinical evidence
Pooled clinical performance data from documented use of robotic TMS protocols. Figures reflect standardized endpoint definitions and are reported per standardized clinical documentation procedures.
Therapeutic response
Patients meeting response criteria on validated depression rating scales after a completed acute treatment course.
Remission rate
Patients reaching remission threshold at end of the documented treatment protocol.
Adverse event profile
Treatment-related adverse events reported as mild and self-limited under standardized pharmacovigilance reporting.
Targeting consistency
Improvement in inter-session coil placement consistency relative to manual operator positioning.
Research Momentum
The next decade of rTMS will be won by precision and proof
Publication output on rTMS is accelerating, and personalized-targeting research is growing faster than any other area. Orion is built to make every treatment more targeted, reproducible, measurable and clinically reviewable.
rTMS publications per year
+21.5% 2024→2025 · 15.2% CAGR
Personalized targeting
+54% over 2023–25 · 24.0% CAGR
Navigation / neuronavigation
+42% over 2023–25 · 19.3% CAGR
Source: PubMed title/abstract search, publication years 2023–2025. Counts are database- and query-dependent.
Deliver precisely. Learn responsibly. Scale clinically.
Roadmap
A Future-Proof Neuromodulation Platform
Orion is an expandable platform that evolves with clinical practice and emerging neuroscience technologies, so your investment today becomes the foundation for tomorrow's capabilities.
Today
Robotic positioning, optical tracking, MRI & MRI-less navigation
Near-Term
Motor threshold mapping, EMG integration, electric field modeling
Advanced
EEG integration, AI-assisted target selection
Future
Advanced research modules, cloud-based reporting
Roadmap items describe planned development and are subject to change.
The PTCR approach
Personalized
Informed by the individual
Targeted
Delivered to the intended brain target
Closed-loop
Guided by measurement and feedback
Robotic
Reproducible spatial control
Clinical Applications
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